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Nov 12

AdaIR: Adaptive All-in-One Image Restoration via Frequency Mining and Modulation

In the image acquisition process, various forms of degradation, including noise, haze, and rain, are frequently introduced. These degradations typically arise from the inherent limitations of cameras or unfavorable ambient conditions. To recover clean images from degraded versions, numerous specialized restoration methods have been developed, each targeting a specific type of degradation. Recently, all-in-one algorithms have garnered significant attention by addressing different types of degradations within a single model without requiring prior information of the input degradation type. However, these methods purely operate in the spatial domain and do not delve into the distinct frequency variations inherent to different degradation types. To address this gap, we propose an adaptive all-in-one image restoration network based on frequency mining and modulation. Our approach is motivated by the observation that different degradation types impact the image content on different frequency subbands, thereby requiring different treatments for each restoration task. Specifically, we first mine low- and high-frequency information from the input features, guided by the adaptively decoupled spectra of the degraded image. The extracted features are then modulated by a bidirectional operator to facilitate interactions between different frequency components. Finally, the modulated features are merged into the original input for a progressively guided restoration. With this approach, the model achieves adaptive reconstruction by accentuating the informative frequency subbands according to different input degradations. Extensive experiments demonstrate that the proposed method achieves state-of-the-art performance on different image restoration tasks, including denoising, dehazing, deraining, motion deblurring, and low-light image enhancement. Our code is available at https://github.com/c-yn/AdaIR.

  • 6 authors
·
Mar 21, 2024 2

Conditional Denoising Diffusion Model-Based Robust MR Image Reconstruction from Highly Undersampled Data

Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can accelerate image acquisition, they often result in image artifacts and degraded quality. Recent diffusion models have shown promise for reconstructing high-fidelity images from undersampled data by learning powerful image priors; however, most existing approaches either (i) rely on unsupervised score functions without paired supervision or (ii) apply data consistency only as a post-processing step. In this work, we introduce a conditional denoising diffusion framework with iterative data-consistency correction, which differs from prior methods by embedding the measurement model directly into every reverse diffusion step and training the model on paired undersampled-ground truth data. This hybrid design bridges generative flexibility with explicit enforcement of MRI physics. Experiments on the fastMRI dataset demonstrate that our framework consistently outperforms recent state-of-the-art deep learning and diffusion-based methods in SSIM, PSNR, and LPIPS, with LPIPS capturing perceptual improvements more faithfully. These results demonstrate that integrating conditional supervision with iterative consistency updates yields substantial improvements in both pixel-level fidelity and perceptual realism, establishing a principled and practical advance toward robust, accelerated MRI reconstruction.

  • 6 authors
·
Oct 7, 2025

Enhancing a Convolutional Autoencoder with a Quantum Approximate Optimization Algorithm for Image Noise Reduction

Image denoising is essential for removing noise in images caused by electric device malfunctions or other factors during image acquisition. It helps preserve image quality and interpretation. Many convolutional autoencoder algorithms have proven effective in image denoising. Owing to their promising efficiency, quantum computers have gained popularity. This study introduces a quantum convolutional autoencoder (QCAE) method for improved image denoising. This method was developed by substituting the representative latent space of the autoencoder with a quantum circuit. To enhance efficiency, we leveraged the advantages of the quantum approximate optimization algorithm (QAOA)-incorporated parameter-shift rule to identify an optimized cost function, facilitating effective learning from data and gradient computation on an actual quantum computer. The proposed QCAE method outperformed its classical counterpart as it exhibited lower training loss and a higher structural similarity index (SSIM) value. QCAE also outperformed its classical counterpart in denoising the MNIST dataset by up to 40% in terms of SSIM value, confirming its enhanced capabilities in real-world applications. Evaluation of QAOA performance across different circuit configurations and layer variations showed that our technique outperformed other circuit designs by 25% on average.

  • 4 authors
·
Jan 11, 2024

SynthStrip: Skull-Stripping for Any Brain Image

The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as skull-stripping, is an integral component of many neuroimage analysis streams. Despite their abundance, popular classical skull-stripping methods are usually tailored to images with specific acquisition properties, namely near-isotropic resolution and T1-weighted (T1w) MRI contrast, which are prevalent in research settings. As a result, existing tools tend to adapt poorly to other image types, such as stacks of thick slices acquired with fast spin-echo (FSE) MRI that are common in the clinic. While learning-based approaches for brain extraction have gained traction in recent years, these methods face a similar burden, as they are only effective for image types seen during the training procedure. To achieve robust skull-stripping across a landscape of imaging protocols, we introduce SynthStrip, a rapid, learning-based brain-extraction tool. By leveraging anatomical segmentations to generate an entirely synthetic training dataset with anatomies, intensity distributions, and artifacts that far exceed the realistic range of medical images, SynthStrip learns to successfully generalize to a variety of real acquired brain images, removing the need for training data with target contrasts. We demonstrate the efficacy of SynthStrip for a diverse set of image acquisitions and resolutions across subject populations, ranging from newborn to adult. We show substantial improvements in accuracy over popular skull-stripping baselines -- all with a single trained model. Our method and labeled evaluation data are available at https://w3id.org/synthstrip.

  • 5 authors
·
Mar 18, 2022

SKM-TEA: A Dataset for Accelerated MRI Reconstruction with Dense Image Labels for Quantitative Clinical Evaluation

Magnetic resonance imaging (MRI) is a cornerstone of modern medical imaging. However, long image acquisition times, the need for qualitative expert analysis, and the lack of (and difficulty extracting) quantitative indicators that are sensitive to tissue health have curtailed widespread clinical and research studies. While recent machine learning methods for MRI reconstruction and analysis have shown promise for reducing this burden, these techniques are primarily validated with imperfect image quality metrics, which are discordant with clinically-relevant measures that ultimately hamper clinical deployment and clinician trust. To mitigate this challenge, we present the Stanford Knee MRI with Multi-Task Evaluation (SKM-TEA) dataset, a collection of quantitative knee MRI (qMRI) scans that enables end-to-end, clinically-relevant evaluation of MRI reconstruction and analysis tools. This 1.6TB dataset consists of raw-data measurements of ~25,000 slices (155 patients) of anonymized patient MRI scans, the corresponding scanner-generated DICOM images, manual segmentations of four tissues, and bounding box annotations for sixteen clinically relevant pathologies. We provide a framework for using qMRI parameter maps, along with image reconstructions and dense image labels, for measuring the quality of qMRI biomarker estimates extracted from MRI reconstruction, segmentation, and detection techniques. Finally, we use this framework to benchmark state-of-the-art baselines on this dataset. We hope our SKM-TEA dataset and code can enable a broad spectrum of research for modular image reconstruction and image analysis in a clinically informed manner. Dataset access, code, and benchmarks are available at https://github.com/StanfordMIMI/skm-tea.

  • 12 authors
·
Mar 13, 2022

Fast Training Data Acquisition for Object Detection and Segmentation using Black Screen Luminance Keying

Deep Neural Networks (DNNs) require large amounts of annotated training data for a good performance. Often this data is generated using manual labeling (error-prone and time-consuming) or rendering (requiring geometry and material information). Both approaches make it difficult or uneconomic to apply them to many small-scale applications. A fast and straightforward approach of acquiring the necessary training data would allow the adoption of deep learning to even the smallest of applications. Chroma keying is the process of replacing a color (usually blue or green) with another background. Instead of chroma keying, we propose luminance keying for fast and straightforward training image acquisition. We deploy a black screen with high light absorption (99.99\%) to record roughly 1-minute long videos of our target objects, circumventing typical problems of chroma keying, such as color bleeding or color overlap between background color and object color. Next we automatically mask our objects using simple brightness thresholding, saving the need for manual annotation. Finally, we automatically place the objects on random backgrounds and train a 2D object detector. We do extensive evaluation of the performance on the widely-used YCB-V object set and compare favourably to other conventional techniques such as rendering, without needing 3D meshes, materials or any other information of our target objects and in a fraction of the time needed for other approaches. Our work demonstrates highly accurate training data acquisition allowing to start training state-of-the-art networks within minutes.

  • 5 authors
·
May 13, 2024

FluoroSAM: A Language-promptable Foundation Model for Flexible X-ray Image Segmentation

Language promptable X-ray image segmentation would enable greater flexibility for human-in-the-loop workflows in diagnostic and interventional precision medicine. Prior efforts have contributed task-specific models capable of solving problems within a narrow scope, but expanding to broader use requires additional data, annotations, and training time. Recently, language-aligned foundation models (LFMs) -- machine learning models trained on large amounts of highly variable image and text data thus enabling broad applicability -- have emerged as promising tools for automated image analysis. Existing foundation models for medical image analysis focus on scenarios and modalities where large, richly annotated datasets are available. However, the X-ray imaging modality features highly variable image appearance and applications, from diagnostic chest X-rays to interventional fluoroscopy, with varying availability of data. To pave the way toward an LFM for comprehensive and language-aligned analysis of arbitrary medical X-ray images, we introduce FluoroSAM, a language-promptable variant of the Segment Anything Model, trained from scratch on 3M synthetic X-ray images from a wide variety of human anatomies, imaging geometries, and viewing angles. These include pseudo-ground truth masks for 128 organ types and 464 tools with associated text descriptions. FluoroSAM is capable of segmenting myriad anatomical structures and tools based on natural language prompts, thanks to the novel incorporation of vector quantization (VQ) of text embeddings in the training process. We demonstrate FluoroSAM's performance quantitatively on real X-ray images and showcase on several applications how FluoroSAM is a key enabler for rich human-machine interaction in the X-ray image acquisition and analysis context. Code is available at https://github.com/arcadelab/fluorosam.

  • 8 authors
·
Mar 12, 2024

Skin disease diagnosis with deep learning: a review

Skin cancer is one of the most threatening diseases worldwide. However, diagnosing skin cancer correctly is challenging. Recently, deep learning algorithms have emerged to achieve excellent performance on various tasks. Particularly, they have been applied to the skin disease diagnosis tasks. In this paper, we present a review on deep learning methods and their applications in skin disease diagnosis. We first present a brief introduction to skin diseases and image acquisition methods in dermatology, and list several publicly available skin datasets for training and testing algorithms. Then, we introduce the conception of deep learning and review popular deep learning architectures. Thereafter, popular deep learning frameworks facilitating the implementation of deep learning algorithms and performance evaluation metrics are presented. As an important part of this article, we then review the literature involving deep learning methods for skin disease diagnosis from several aspects according to the specific tasks. Additionally, we discuss the challenges faced in the area and suggest possible future research directions. The major purpose of this article is to provide a conceptual and systematically review of the recent works on skin disease diagnosis with deep learning. Given the popularity of deep learning, there remains great challenges in the area, as well as opportunities that we can explore in the future.

  • 4 authors
·
Nov 11, 2020 2

A New Dataset and Performance Benchmark for Real-time Spacecraft Segmentation in Onboard Flight Computers

Spacecraft deployed in outer space are routinely subjected to various forms of damage due to exposure to hazardous environments. In addition, there are significant risks to the subsequent process of in-space repairs through human extravehicular activity or robotic manipulation, incurring substantial operational costs. Recent developments in image segmentation could enable the development of reliable and cost-effective autonomous inspection systems. While these models often require large amounts of training data to achieve satisfactory results, publicly available annotated spacecraft segmentation data are very scarce. Here, we present a new dataset of nearly 64k annotated spacecraft images that was created using real spacecraft models, superimposed on a mixture of real and synthetic backgrounds generated using NASA's TTALOS pipeline. To mimic camera distortions and noise in real-world image acquisition, we also added different types of noise and distortion to the images. Finally, we finetuned YOLOv8 and YOLOv11 segmentation models to generate performance benchmarks for the dataset under well-defined hardware and inference time constraints to mimic real-world image segmentation challenges for real-time onboard applications in space on NASA's inspector spacecraft. The resulting models, when tested under these constraints, achieved a Dice score of 0.92, Hausdorff distance of 0.69, and an inference time of about 0.5 second. The dataset and models for performance benchmark are available at https://github.com/RiceD2KLab/SWiM.

  • 9 authors
·
Jul 14, 2025

US-VLA: An Ultrasound Vision-Language-Action Model for Embodied Abdomina

Artificial intelligence-assisted ultrasound scanning enhances diagnostic reliability and efficiency by providing real-time guidance for standardized image acquisition and reducing operator dependence. However, existing reinforcement learning and learning-assisted ultrasound scanning methods typically rely on carefully designed reward functions or extensive interaction data, which limits their generalization ability and stability across different devices, patient populations, and complex clinical scenarios. To address these challenges, we propose an ultrasound vision-language-action model (US-VLA) for automated ultrasound scanning that explicitly encodes clinical semantic goals and generates sequential probe manipulation actions under real-time ultrasound feedback. In particular, we first design an ultrasound-aware expert fusion module to jointly integrate ultrasound observations with auxiliary contextual information, enabling semantic ultrasound feedback to effectively guide the scanning process. Then, we construct US-VLA-Data, a real-world dataset covering liver and kidney examinations, which includes five clinically defined standard planes and comprises 320 expert scanning trajectories with approximately 80,000 synchronized timesteps. Extensive experiments demonstrate that US-VLA achieves competitive performance in ultrasound probe manipulation tasks, indicating its effectiveness and promising generalization within the evaluated abdominal ultrasound setting. The source code is available at https://github.com/VMVLab/US-VLA.

  • 7 authors
·
Aug 16

Adapting Vehicle Detectors for Aerial Imagery to Unseen Domains with Weak Supervision

Detecting vehicles in aerial imagery is a critical task with applications in traffic monitoring, urban planning, and defense intelligence. Deep learning methods have provided state-of-the-art (SOTA) results for this application. However, a significant challenge arises when models trained on data from one geographic region fail to generalize effectively to other areas. Variability in factors such as environmental conditions, urban layouts, road networks, vehicle types, and image acquisition parameters (e.g., resolution, lighting, and angle) leads to domain shifts that degrade model performance. This paper proposes a novel method that uses generative AI to synthesize high-quality aerial images and their labels, improving detector training through data augmentation. Our key contribution is the development of a multi-stage, multi-modal knowledge transfer framework utilizing fine-tuned latent diffusion models (LDMs) to mitigate the distribution gap between the source and target environments. Extensive experiments across diverse aerial imagery domains show consistent performance improvements in AP50 over supervised learning on source domain data, weakly supervised adaptation methods, unsupervised domain adaptation methods, and open-set object detectors by 4-23%, 6-10%, 7-40%, and more than 50%, respectively. Furthermore, we introduce two newly annotated aerial datasets from New Zealand and Utah to support further research in this field. Project page is available at: https://humansensinglab.github.io/AGenDA

PrediTree: A Multi-Temporal Sub-meter Dataset of Multi-Spectral Imagery Aligned With Canopy Height Maps

We present PrediTree, the first comprehensive open-source dataset designed for training and evaluating tree height prediction models at sub-meter resolution. This dataset combines very high-resolution (0.5m) LiDAR-derived canopy height maps, spatially aligned with multi-temporal and multi-spectral imagery, across diverse forest ecosystems in France, totaling 3,141,568 images. PrediTree addresses a critical gap in forest monitoring capabilities by enabling the training of deep learning methods that can predict tree growth based on multiple past observations. %Initially focused on French forests, PrediTree is designed as an expanding resource with ongoing efforts to incorporate data from other countries. To make use of this PrediTree dataset, we propose an encoder-decoder framework that requires the multi-temporal multi-spectral imagery and the relative time differences in years between the canopy height map timestamp (target) and each image acquisition date for which this framework predicts the canopy height. The conducted experiments demonstrate that a U-Net architecture trained on the PrediTree dataset provides the highest masked mean squared error of 11.78%, outperforming the next-best architecture, ResNet-50, by around 12%, and cutting the error of the same experiments but on fewer bands (red, green, blue only), by around 30%. This dataset is publicly available on URL{HuggingFace}, and both processing and training codebases are available on URL{GitHub}.

  • 3 authors
·
Sep 1, 2025

SingRef6D: Monocular Novel Object Pose Estimation with a Single RGB Reference

Recent 6D pose estimation methods demonstrate notable performance but still face some practical limitations. For instance, many of them rely heavily on sensor depth, which may fail with challenging surface conditions, such as transparent or highly reflective materials. In the meantime, RGB-based solutions provide less robust matching performance in low-light and texture-less scenes due to the lack of geometry information. Motivated by these, we propose SingRef6D, a lightweight pipeline requiring only a single RGB image as a reference, eliminating the need for costly depth sensors, multi-view image acquisition, or training view synthesis models and neural fields. This enables SingRef6D to remain robust and capable even under resource-limited settings where depth or dense templates are unavailable. Our framework incorporates two key innovations. First, we propose a token-scaler-based fine-tuning mechanism with a novel optimization loss on top of Depth-Anything v2 to enhance its ability to predict accurate depth, even for challenging surfaces. Our results show a 14.41% improvement (in δ_{1.05}) on REAL275 depth prediction compared to Depth-Anything v2 (with fine-tuned head). Second, benefiting from depth availability, we introduce a depth-aware matching process that effectively integrates spatial relationships within LoFTR, enabling our system to handle matching for challenging materials and lighting conditions. Evaluations of pose estimation on the REAL275, ClearPose, and Toyota-Light datasets show that our approach surpasses state-of-the-art methods, achieving a 6.1% improvement in average recall.

  • 6 authors
·
Sep 26, 2025

AI-Assisted Cervical Cancer Screening

Visual Inspection with Acetic Acid (VIA) remains the most feasible cervical cancer screening test in resource-constrained settings of low- and middle-income countries (LMICs), which are often performed screening camps or primary/community health centers by nurses instead of the preferred but unavailable expert Gynecologist. To address the highly subjective nature of the test, various handheld devices integrating cameras or smartphones have been recently explored to capture cervical images during VIA and aid decision-making via telemedicine or AI models. Most studies proposing AI models retrospectively use a relatively small number of already collected images from specific devices, digital cameras, or smartphones; the challenges and protocol for quality image acquisition during VIA in resource-constrained camp settings, challenges in getting gold standard, data imbalance, etc. are often overlooked. We present a novel approach and describe the end-to-end design process to build a robust smartphone-based AI-assisted system that does not require buying a separate integrated device: the proposed protocol for quality image acquisition in resource-constrained settings, dataset collected from 1,430 women during VIA performed by nurses in screening camps, preprocessing pipeline, and training and evaluation of a deep-learning-based classification model aimed to identify (pre)cancerous lesions. Our work shows that the readily available smartphones and a suitable protocol can capture the cervix images with the required details for the VIA test well; the deep-learning-based classification model provides promising results to assist nurses in VIA screening; and provides a direction for large-scale data collection and validation in resource-constrained settings.

  • 6 authors
·
Sep 3, 2024

Deblurring 3D Gaussian Splatting

Recent studies in Radiance Fields have paved the robust way for novel view synthesis with their photorealistic rendering quality. Nevertheless, they usually employ neural networks and volumetric rendering, which are costly to train and impede their broad use in various real-time applications due to the lengthy rendering time. Lately 3D Gaussians splatting-based approach has been proposed to model the 3D scene, and it achieves remarkable visual quality while rendering the images in real-time. However, it suffers from severe degradation in the rendering quality if the training images are blurry. Blurriness commonly occurs due to the lens defocusing, object motion, and camera shake, and it inevitably intervenes in clean image acquisition. Several previous studies have attempted to render clean and sharp images from blurry input images using neural fields. The majority of those works, however, are designed only for volumetric rendering-based neural radiance fields and are not straightforwardly applicable to rasterization-based 3D Gaussian splatting methods. Thus, we propose a novel real-time deblurring framework, deblurring 3D Gaussian Splatting, using a small Multi-Layer Perceptron (MLP) that manipulates the covariance of each 3D Gaussian to model the scene blurriness. While deblurring 3D Gaussian Splatting can still enjoy real-time rendering, it can reconstruct fine and sharp details from blurry images. A variety of experiments have been conducted on the benchmark, and the results have revealed the effectiveness of our approach for deblurring. Qualitative results are available at https://benhenryl.github.io/Deblurring-3D-Gaussian-Splatting/

  • 5 authors
·
Jan 1, 2024

Complex-valued neural networks to speed-up MR Thermometry during Hyperthermia using Fourier PD and PDUNet

Hyperthermia (HT) in combination with radio- and/or chemotherapy has become an accepted cancer treatment for distinct solid tumour entities. In HT, tumour tissue is exogenously heated to temperatures between 39 and 43 ^circC for 60 minutes. Temperature monitoring can be performed non-invasively using dynamic magnetic resonance imaging (MRI). However, the slow nature of MRI leads to motion artefacts in the images due to the movements of patients during image acquisition. By discarding parts of the data, the speed of the acquisition can be increased - known as undersampling. However, due to the invalidation of the Nyquist criterion, the acquired images might be blurry and can also produce aliasing artefacts. The aim of this work was, therefore, to reconstruct highly undersampled MR thermometry acquisitions with better resolution and with fewer artefacts compared to conventional methods. The use of deep learning in the medical field has emerged in recent times, and various studies have shown that deep learning has the potential to solve inverse problems such as MR image reconstruction. However, most of the published work only focuses on the magnitude images, while the phase images are ignored, which are fundamental requirements for MR thermometry. This work, for the first time, presents deep learning-based solutions for reconstructing undersampled MR thermometry data. Two different deep learning models have been employed here, the Fourier Primal-Dual network and the Fourier Primal-Dual UNet, to reconstruct highly undersampled complex images of MR thermometry. The method reduced the temperature difference between the undersampled MRIs and the fully sampled MRIs from 1.3 ^circC to 0.6 ^circC in full volume and 0.49 ^circC to 0.06 ^circC in the tumour region for an acceleration factor of 10.

  • 9 authors
·
Oct 2, 2023

ReconResNet: Regularised Residual Learning for MR Image Reconstruction of Undersampled Cartesian and Radial Data

MRI is an inherently slow process, which leads to long scan time for high-resolution imaging. The speed of acquisition can be increased by ignoring parts of the data (undersampling). Consequently, this leads to the degradation of image quality, such as loss of resolution or introduction of image artefacts. This work aims to reconstruct highly undersampled Cartesian or radial MR acquisitions, with better resolution and with less to no artefact compared to conventional techniques like compressed sensing. In recent times, deep learning has emerged as a very important area of research and has shown immense potential in solving inverse problems, e.g. MR image reconstruction. In this paper, a deep learning based MR image reconstruction framework is proposed, which includes a modified regularised version of ResNet as the network backbone to remove artefacts from the undersampled image, followed by data consistency steps that fusions the network output with the data already available from undersampled k-space in order to further improve reconstruction quality. The performance of this framework for various undersampling patterns has also been tested, and it has been observed that the framework is robust to deal with various sampling patterns, even when mixed together while training, and results in very high quality reconstruction, in terms of high SSIM (highest being 0.990pm0.006 for acceleration factor of 3.5), while being compared with the fully sampled reconstruction. It has been shown that the proposed framework can successfully reconstruct even for an acceleration factor of 20 for Cartesian (0.968pm0.005) and 17 for radially (0.962pm0.012) sampled data. Furthermore, it has been shown that the framework preserves brain pathology during reconstruction while being trained on healthy subjects.

  • 7 authors
·
Mar 16, 2021

Towards a satellite image manipulation and deepfake localization benchmark dataset

Verifying the authenticity of satellite imagery has become increasingly critical given advances in generative artificial intelligence. Highly realistic synthetic imagery produced for malicious purposes (deepfakes) can have major consequences in the remote sensing domain, where this data is a fundamental source of information for science applications, planning, logistics, and monitoring. The remote sensing community lacks high-quality, fine-grained manipulation datasets suitable for training and evaluating detection and image forensics algorithms. Existing datasets are lacking and those that do exist either provide no ground truth masks for evaluating manipulation localization, or consist of entire images generated by GANs or diffusion models, which are inadequate for measuring localization performance. To address this gap, we describe a preliminary dataset construction process and prototype benchmark dataset for satellite image manipulation detection and localization. The dataset contains 60 images total, with 30 images carefully manipulated using three manipulation types including copy-paste splicing and diffusion model inpainting, and 30 authentic images. Each image is accompanied by a ground-truth mask and acquisition metadata, enabling both pixel-level localization metrics, image metadata studies, and analyses of how manipulation detection performance relates to image collection parameters. We describe the dataset construction process and present this initial release to support further research in image forensics and geospatial deepfake detection. The prototype dataset can be downloaded at https://huggingface.co/datasets/geodf/fmow-fake-small.

  • 4 authors
·
Aug 4

PhyMRI-SR: Toward Physics-Aware MRI Image Super-Resolution

Magnetic resonance imaging (MRI) super-resolution is vital for improving diagnostic accessibility, yet most methods treat it as a deterministic mapping from a fixed low-resolution input to a high-resolution target. This overlooks a key property of MRI acquisition physics: spatial resolution and signal-to-noise ratio (SNR) are inherently coupled, making any given low-resolution scan merely one of many possible realizations under varying acquisition trade-offs. We rethink MRI super-resolution as a physics-aware reconstruction problem, in which the goal is to identify the optimal resolution-SNR configuration and then super-resolve it to obtain high-quality MRI results. A key implication of this formulation is that MRI resolution becomes dynamic rather than fixed. To handle such resolution-heterogeneous inputs, we adapt 2D Gaussian Splatting (2D GS) to MRI by formulating reconstruction as a coordinate-based, resolution-agnostic rendering problem. To further enhance fidelity, we introduce three innovations: (1) a prior-aware Gaussian representation that combines an Anatomical Structure Prior for tissue-specific kernel initialization with an Imaging System Prior that captures hardware characteristics via a covariance dictionary; (2) a physics-constrained signal modeling scheme that predicts intrinsic tissue parameters (proton density rho and effective relaxation rate R2) and synthesizes intensities through governing physical equations, ensuring biophysically plausible contrast; and (3) a meta-learning framework that alleviates paired-data scarcity by pretraining on simulated data and adapting to real-world conditions. Extensive experiments on dynamic-resolution datasets and standard benchmarks demonstrate that our method achieves state-of-the-art performance, highlighting its strong potential for clinical deployment.

Agent Skill Acquisition for Large Language Models via CycleQD

Training large language models to acquire specific skills remains a challenging endeavor. Conventional training approaches often struggle with data distribution imbalances and inadequacies in objective functions that do not align well with task-specific performance. To address these challenges, we introduce CycleQD, a novel approach that leverages the Quality Diversity framework through a cyclic adaptation of the algorithm, along with a model merging based crossover and an SVD-based mutation. In CycleQD, each task's performance metric is alternated as the quality measure while the others serve as the behavioral characteristics. This cyclic focus on individual tasks allows for concentrated effort on one task at a time, eliminating the need for data ratio tuning and simplifying the design of the objective function. Empirical results from AgentBench indicate that applying CycleQD to LLAMA3-8B-INSTRUCT based models not only enables them to surpass traditional fine-tuning methods in coding, operating systems, and database tasks, but also achieves performance on par with GPT-3.5-TURBO, which potentially contains much more parameters, across these domains. Crucially, this enhanced performance is achieved while retaining robust language capabilities, as evidenced by its performance on widely adopted language benchmark tasks. We highlight the key design choices in CycleQD, detailing how these contribute to its effectiveness. Furthermore, our method is general and can be applied to image segmentation models, highlighting its applicability across different domains.

  • 4 authors
·
Oct 16, 2024

Webly-Supervised Image Manipulation Localization via Category-Aware Auto-Annotation

Images manipulated using image editing tools can mislead viewers and pose significant risks to social security. However, accurately localizing the manipulated regions within an image remains a challenging problem. One of the main barriers in this area is the high cost of data acquisition and the severe lack of high-quality annotated datasets. To address this challenge, we introduce novel methods that mitigate data scarcity by leveraging readily available web data. We utilize a large collection of manually forged images from the web, as well as automatically generated annotations derived from a simpler auxiliary task, constrained image manipulation localization. Specifically, we introduce a new paradigm CAAAv2, which automatically and accurately annotates manipulated regions at the pixel level. To further improve annotation quality, we propose a novel metric, QES, which filters out unreliable annotations. Through CAAA v2 and QES, we construct MIMLv2, a large-scale, diverse, and high-quality dataset containing 246,212 manually forged images with pixel-level mask annotations. This is over 120x larger than existing handcrafted datasets like IMD20. Additionally, we introduce Object Jitter, a technique that further enhances model training by generating high-quality manipulation artifacts. Building on these advances, we develop a new model, Web-IML, designed to effectively leverage web-scale supervision for the image manipulation localization task. Extensive experiments demonstrate that our approach substantially alleviates the data scarcity problem and significantly improves the performance of various models on multiple real-world forgery benchmarks. With the proposed web supervision, Web-IML achieves a striking performance gain of 31% and surpasses previous SOTA TruFor by 24.1 average IoU points. The dataset and code will be made publicly available at https://github.com/qcf-568/MIML.

  • 4 authors
·
Aug 28, 2025

HSIGene: A Foundation Model For Hyperspectral Image Generation

Hyperspectral image (HSI) plays a vital role in various fields such as agriculture and environmental monitoring. However, due to the expensive acquisition cost, the number of hyperspectral images is limited, degenerating the performance of downstream tasks. Although some recent studies have attempted to employ diffusion models to synthesize HSIs, they still struggle with the scarcity of HSIs, affecting the reliability and diversity of the generated images. Some studies propose to incorporate multi-modal data to enhance spatial diversity, but the spectral fidelity cannot be ensured. In addition, existing HSI synthesis models are typically uncontrollable or only support single-condition control, limiting their ability to generate accurate and reliable HSIs. To alleviate these issues, we propose HSIGene, a novel HSI generation foundation model which is based on latent diffusion and supports multi-condition control, allowing for more precise and reliable HSI generation. To enhance the spatial diversity of the training data while preserving spectral fidelity, we propose a new data augmentation method based on spatial super-resolution, in which HSIs are upscaled first, and thus abundant training patches could be obtained by cropping the high-resolution HSIs. In addition, to improve the perceptual quality of the augmented data, we introduce a novel two-stage HSI super-resolution framework, which first applies RGB bands super-resolution and then utilizes our proposed Rectangular Guided Attention Network (RGAN) for guided HSI super-resolution. Experiments demonstrate that the proposed model is capable of generating a vast quantity of realistic HSIs for downstream tasks such as denoising and super-resolution. The code and models are available at https://github.com/LiPang/HSIGene.

  • 7 authors
·
Sep 19, 2024

Latent Diffusion Model for Medical Image Standardization and Enhancement

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT scanners and customized acquisition protocols can introduce significant inconsistencies in texture features, even when assessing the same patient. This variability poses a fundamental challenge for subsequent research that relies on consistent image features. Existing CT image standardization models predominantly utilize GAN-based supervised or semi-supervised learning, but their performance remains limited. We present DiffusionCT, an innovative score-based DDPM model that operates in the latent space to transform disparate non-standard distributions into a standardized form. The architecture comprises a U-Net-based encoder-decoder, augmented by a DDPM model integrated at the bottleneck position. First, the encoder-decoder is trained independently, without embedding DDPM, to capture the latent representation of the input data. Second, the latent DDPM model is trained while keeping the encoder-decoder parameters fixed. Finally, the decoder uses the transformed latent representation to generate a standardized CT image, providing a more consistent basis for downstream analysis. Empirical tests on patient CT images indicate notable improvements in image standardization using DiffusionCT. Additionally, the model significantly reduces image noise in SPAD images, further validating the effectiveness of DiffusionCT for advanced imaging tasks.

  • 7 authors
·
Oct 8, 2023

The role of self-supervised pretraining in differentially private medical image analysis

Differential privacy (DP) provides formal protection for sensitive data but typically incurs substantial losses in diagnostic performance. Model initialization has emerged as a critical factor in mitigating this degradation, yet the role of modern self-supervised learning under full-model DP remains poorly understood. Here, we present a large-scale evaluation of initialization strategies for differentially private medical image analysis, using chest radiograph classification as a representative benchmark with more than 800,000 images. Using state-of-the-art ConvNeXt models trained with DP-SGD across realistic privacy regimes, we compare non-domain-specific supervised ImageNet initialization, non-domain-specific self-supervised DINOv3 initialization, and domain-specific supervised pretraining on MIMIC-CXR, the largest publicly available chest radiograph dataset. Evaluations are conducted across five external datasets spanning diverse institutions and acquisition settings. We show that DINOv3 initialization consistently improves diagnostic utility relative to ImageNet initialization under DP, but remains inferior to domain-specific supervised pretraining, which achieves performance closest to non-private baselines. We further demonstrate that initialization choice strongly influences demographic fairness, cross-dataset generalization, and robustness to data scale and model capacity under privacy constraints. The results establish initialization strategy as a central determinant of utility, fairness, and generalization in differentially private medical imaging.

  • 10 authors
·
Jan 27

Baseline Method of the Foundation Model Challenge for Ultrasound Image Analysis

Ultrasound (US) imaging exhibits substantial heterogeneity across anatomical structures and acquisition protocols, posing significant challenges to the development of generalizable analysis models. Most existing methods are task-specific, limiting their suitability as clinically deployable foundation models. To address this limitation, the Foundation Model Challenge for Ultrasound Image Analysis (FM\_UIA~2026) introduces a large-scale multi-task benchmark comprising 27 subtasks across segmentation, classification, detection, and regression. In this paper, we present the official baseline for FM\_UIA~2026 based on a unified Multi-Head Multi-Task Learning (MH-MTL) framework that supports all tasks within a single shared network. The model employs an ImageNet-pretrained EfficientNet--B4 backbone for robust feature extraction, combined with a Feature Pyramid Network (FPN) to capture multi-scale contextual information. A task-specific routing strategy enables global tasks to leverage high-level semantic features, while dense prediction tasks exploit spatially detailed FPN representations. Training incorporates a composite loss with task-adaptive learning rate scaling and a cosine annealing schedule. Validation results demonstrate the feasibility and robustness of this unified design, establishing a strong and extensible baseline for ultrasound foundation model research. The code and dataset are publicly available at https://github.com/lijiake2408/Foundation-Model-Challenge-for-Ultrasound-Image-Analysis{GitHub}.

  • 10 authors
·
Feb 1

Global displacement induced by rigid motion simulation during MRI acquisition

Purpose: Simulation of motion in the frequency domain during the MRI acquisition process is an important tool to study the effect of object motion. It is natural in this context to rely on a voxel-to-voxel difference metric between the original image and its motion-simulated version to quantify the alteration. These metrics are very sensitive to any mis-coregistration between the two images. As we observed global displacements of the corrupted image for specific simulated motions, we focused this work on the critical choice of a reference position of the object for the motion simulation that avoids any global displacement. Methods: We used the motion simulation framework and we studied the different proposed solutions. Classically, the position around the k-space center is considered as a reference with two analytical solutions to correct for global image shifts: demeaning the image in the Fourier domain either using the exact position at k-space center or using a weighted average around the center. Results: We demonstrated with motion simulated examples that these analytical solutions did not yield the same results as a direct co-registration method. Indeed, short transitions around the k-space center did not induce any global displacement, in contrast with what both analytical solutions assumed. We also observed a dependence of the global shift to both the motion amplitude and the translation direction. Conclusion: In the absence of a theoretical solution, we concluded that an extra co-registration step after motion simulation was needed in order to compare the simulation with its reference image.

  • 4 authors
·
Apr 6, 2022

MedGSSR: Generalizable Medical Image Super-Resolution 3D Reconstruction via Hierarchical Feed-forward Gaussian Splatting

High-resolution volumetric medical imaging is critical for clinical diagnosis, yet acquisition is often limited by scanner hardware, scan time, and for CT, radiation dose. Medical 3D Super-Resolution (Med3DSR) offers a computational alternative, but existing methods commonly rely on per-subject optimization, pretrained priors, or coordinate-based implicit representations, which compromise anatomical fidelity and limit efficiency. To address these limitations, we present MedGSSR, a fully end-to-end feed-forward framework that represents volumes as an explicit 3D Gaussian field for Med3DSR. Unlike coordinate-based implicit functions, our explicit 3D Gaussian representation naturally enhances signal continuity and local high-frequency fidelity. Specifically, MedGSSR explicitly decouples the reconstruction process into coarse-grained structural preservation and fine-grained textural refinement through the proposed Pyramid Anatomical Encoder and a Hierarchical Gaussian Projector. To support arbitrary-scale super-resolution, we introduce sub-voxel Gaussian decomposition and a Differentiable Gaussian Voxelizer that directly queries the continuous 3D intensity field, reducing discretization artifacts. Extensive experiments on MRI and CT benchmarks demonstrate that MedGSSR significantly outperforms state-of-the-art methods. Notably, our framework exhibits robust generalizability across unseen datasets without requiring per-subject optimization, enabling fast inference and high-fidelity volumetric super-resolution in practical clinical settings. Our project webpage, including code, is at https://william2ai.github.io/medgssr

  • 10 authors
·
Sep 5

3L-D: A Low-Light Level Dataset from a Sensor-Agnostic, Alignment-Preserving Acquisition Framework

Supervised low-light image and video enhancement has achieved remarkable progress, yet current models remain fundamentally constrained by the limitations of existing datasets. Prevailing methods typically rely on uncontrolled ambient captures, camera parameter manipulation (e.g., exposure or ISO adjustments), or neutral density filters, failing to replicate authentic night-sky near-infrared spectral content and genuine low-photon noise distributions. Furthermore, capturing dynamic paired sequences without introducing warping artifacts or sensor-specific biases remains an open challenge. In this paper, we introduce 3L-Dataset, a physically calibrated low-light image and video dataset generated using a modular, sensor-agnostic acquisition framework. Our test bench faithfully reproduces the standardized Midavaine night level scale from Level 1 (full moon, approximately 1000 mlx) down to Level 5 (overcast moonless night, approximately 0.1 mlx), spanning the visible to near-infrared spectrum across diverse realistic environments, including countryside, forest, urban, and desert scale models. Using high-precision programmable mechanical actuation, our acquisition framework guarantees sub-pixel spatial alignment across synchronized sextuplets, each composed of one reference image and five corresponding images acquired at the five standardized night levels, without post-processing image warping. We evaluate multiple representative deep learning baselines across varying night levels, revealing critical trade-offs between reconstruction fidelity, perceptual quality, and inference latency under severe photon starvation. The modular acquisition framework can be adapted to different cameras, optical systems, sensor technologies, and resolutions, enabling the dataset to be continuously expanded.

  • 7 authors
·
Nov 1

EUReCA: End-to-End Unified CBCT Reconstruction Across Clinical Acquisitions

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy, but reducing the number of projections to lower dose and scan time makes reconstruction increasingly ill-posed. We present EUReCA (End-to-end Unified REconstruction across Clinical Acquisitions), a geometry-aware feed-forward model for variable-view clinical linac CBCT. For a given acquisition trajectory, EUReCA accepts 8-100 projections with a single set of weights, without view-count-specific retraining; the same architecture and training recipe extend unchanged to other clinical trajectories. It combines learned projection features with an in-frame Feldkamp-Davis-Kress (FDK) reconstruction. The model encodes each projection with a shared multiscale backbone, back-projects features into multiresolution 3D grids using the acquisition geometry, aggregates variable numbers of views at fixed computational cost, and refines the volume with a global 3D transformer and multilevel decoder. On simulated data, EUReCA achieved 29.9-33.2 dB PSNR with 10-100 views and outperformed all applicable feed-forward baselines; it also exceeded iterative optimization-based methods while running orders of magnitude faster. On 15 measured patient CBCT scans evaluated against vendor reconstructions, EUReCA achieved the best performance at every tested view count. These results suggest that geometry-aware, measurement-anchored feed-forward reconstruction can provide a practical and flexible foundation for variable-view linac CBCT.

  • 11 authors
·
Oct 26

Med3D: Transfer Learning for 3D Medical Image Analysis

The performance on deep learning is significantly affected by volume of training data. Models pre-trained from massive dataset such as ImageNet become a powerful weapon for speeding up training convergence and improving accuracy. Similarly, models based on large dataset are important for the development of deep learning in 3D medical images. However, it is extremely challenging to build a sufficiently large dataset due to difficulty of data acquisition and annotation in 3D medical imaging. We aggregate the dataset from several medical challenges to build 3DSeg-8 dataset with diverse modalities, target organs, and pathologies. To extract general medical three-dimension (3D) features, we design a heterogeneous 3D network called Med3D to co-train multi-domain 3DSeg-8 so as to make a series of pre-trained models. We transfer Med3D pre-trained models to lung segmentation in LIDC dataset, pulmonary nodule classification in LIDC dataset and liver segmentation on LiTS challenge. Experiments show that the Med3D can accelerate the training convergence speed of target 3D medical tasks 2 times compared with model pre-trained on Kinetics dataset, and 10 times compared with training from scratch as well as improve accuracy ranging from 3% to 20%. Transferring our Med3D model on state-the-of-art DenseASPP segmentation network, in case of single model, we achieve 94.6\% Dice coefficient which approaches the result of top-ranged algorithms on the LiTS challenge.

  • 3 authors
·
Apr 1, 2019

Learning 3D Representations from 2D Pre-trained Models via Image-to-Point Masked Autoencoders

Pre-training by numerous image data has become de-facto for robust 2D representations. In contrast, due to the expensive data acquisition and annotation, a paucity of large-scale 3D datasets severely hinders the learning for high-quality 3D features. In this paper, we propose an alternative to obtain superior 3D representations from 2D pre-trained models via Image-to-Point Masked Autoencoders, named as I2P-MAE. By self-supervised pre-training, we leverage the well learned 2D knowledge to guide 3D masked autoencoding, which reconstructs the masked point tokens with an encoder-decoder architecture. Specifically, we first utilize off-the-shelf 2D models to extract the multi-view visual features of the input point cloud, and then conduct two types of image-to-point learning schemes on top. For one, we introduce a 2D-guided masking strategy that maintains semantically important point tokens to be visible for the encoder. Compared to random masking, the network can better concentrate on significant 3D structures and recover the masked tokens from key spatial cues. For another, we enforce these visible tokens to reconstruct the corresponding multi-view 2D features after the decoder. This enables the network to effectively inherit high-level 2D semantics learned from rich image data for discriminative 3D modeling. Aided by our image-to-point pre-training, the frozen I2P-MAE, without any fine-tuning, achieves 93.4% accuracy for linear SVM on ModelNet40, competitive to the fully trained results of existing methods. By further fine-tuning on on ScanObjectNN's hardest split, I2P-MAE attains the state-of-the-art 90.11% accuracy, +3.68% to the second-best, demonstrating superior transferable capacity. Code will be available at https://github.com/ZrrSkywalker/I2P-MAE.

  • 5 authors
·
Dec 13, 2022

FlexiDreamer: Single Image-to-3D Generation with FlexiCubes

3D content generation from text prompts or single images has made remarkable progress in quality and speed recently. One of its dominant paradigms involves generating consistent multi-view images followed by a sparse-view reconstruction. However, due to the challenge of directly deforming the mesh representation to approach the target topology, most methodologies learn an implicit representation (such as NeRF) during the sparse-view reconstruction and acquire the target mesh by a post-processing extraction. Although the implicit representation can effectively model rich 3D information, its training typically entails a long convergence time. In addition, the post-extraction operation from the implicit field also leads to undesirable visual artifacts. In this paper, we propose FlexiDreamer, a novel single image-to-3d generation framework that reconstructs the target mesh in an end-to-end manner. By leveraging a flexible gradient-based extraction known as FlexiCubes, our method circumvents the defects brought by the post-processing and facilitates a direct acquisition of the target mesh. Furthermore, we incorporate a multi-resolution hash grid encoding scheme that progressively activates the encoding levels into the implicit field in FlexiCubes to help capture geometric details for per-step optimization. Notably, FlexiDreamer recovers a dense 3D structure from a single-view image in approximately 1 minute on a single NVIDIA A100 GPU, outperforming previous methodologies by a large margin.

  • 5 authors
·
Apr 1, 2024 2

MUSES: 3D-Controllable Image Generation via Multi-Modal Agent Collaboration

Despite recent advancements in text-to-image generation, most existing methods struggle to create images with multiple objects and complex spatial relationships in 3D world. To tackle this limitation, we introduce a generic AI system, namely MUSES, for 3D-controllable image generation from user queries. Specifically, our MUSES addresses this challenging task by developing a progressive workflow with three key components, including (1) Layout Manager for 2D-to-3D layout lifting, (2) Model Engineer for 3D object acquisition and calibration, (3) Image Artist for 3D-to-2D image rendering. By mimicking the collaboration of human professionals, this multi-modal agent pipeline facilitates the effective and automatic creation of images with 3D-controllable objects, through an explainable integration of top-down planning and bottom-up generation. Additionally, we find that existing benchmarks lack detailed descriptions of complex 3D spatial relationships of multiple objects. To fill this gap, we further construct a new benchmark of T2I-3DisBench (3D image scene), which describes diverse 3D image scenes with 50 detailed prompts. Extensive experiments show the state-of-the-art performance of MUSES on both T2I-CompBench and T2I-3DisBench, outperforming recent strong competitors such as DALL-E 3 and Stable Diffusion 3. These results demonstrate a significant step of MUSES forward in bridging natural language, 2D image generation, and 3D world. Our codes and models will be released soon.

  • 6 authors
·
Aug 20, 2024

Hestia: Voxel-Face-Aware Hierarchical Next-Best-View Acquisition for Efficient 3D Reconstruction

Advances in 3D reconstruction and novel view synthesis have enabled efficient and photorealistic rendering. However, images for reconstruction are still either largely manual or constrained by simple preplanned trajectories. To address this issue, recent works propose generalizable next-best-view planners that do not require online learning. Nevertheless, robustness and performance remain limited across various shapes. Hence, this study introduces Voxel-Face-Aware Hierarchical Next-Best-View Acquisition for Efficient 3D Reconstruction (Hestia), which addresses the shortcomings of the reinforcement learning-based generalizable approaches for five-degree-of-freedom viewpoint prediction. Hestia systematically improves the planners through four components: a more diverse dataset to promote robustness, a hierarchical structure to manage the high-dimensional continuous action search space, a close-greedy strategy to mitigate spurious correlations, and a face-aware design to avoid overlooking geometry. Experimental results show that Hestia achieves non-marginal improvements, with at least a 4% gain in coverage ratio, while reducing Chamfer Distance by 50% and maintaining real-time inference. In addition, Hestia outperforms prior methods by at least 12% in coverage ratio with a 5-image budget and remains robust to object placement variations. Finally, we demonstrate that Hestia, as a next-best-view planner, is feasible for the real-world application. Our project page is https://johnnylu305.github.io/hestia web.

  • 8 authors
·
May 14

AttenCraft: Attention-guided Disentanglement of Multiple Concepts for Text-to-Image Customization

With the unprecedented performance being achieved by text-to-image (T2I) diffusion models, T2I customization further empowers users to tailor the diffusion model to new concepts absent in the pre-training dataset, termed subject-driven generation. Moreover, extracting several new concepts from a single image enables the model to learn multiple concepts, and simultaneously decreases the difficulties of training data preparation, urging the disentanglement of multiple concepts to be a new challenge. However, existing models for disentanglement commonly require pre-determined masks or retain background elements. To this end, we propose an attention-guided method, AttenCraft, for multiple concept disentanglement. In particular, our method leverages self-attention and cross-attention maps to create accurate masks for each concept within a single initialization step, omitting any required mask preparation by humans or other models. The created masks are then applied to guide the cross-attention activation of each target concept during training and achieve concept disentanglement. Additionally, we introduce Uniform sampling and Reweighted sampling schemes to alleviate the non-synchronicity of feature acquisition from different concepts, and improve generation quality. Our method outperforms baseline models in terms of image-alignment, and behaves comparably on text-alignment. Finally, we showcase the applicability of AttenCraft to more complicated settings, such as an input image containing three concepts. The project is available at https://github.com/junjie-shentu/AttenCraft.

  • 3 authors
·
May 28, 2024

HiMTok: Learning Hierarchical Mask Tokens for Image Segmentation with Large Multimodal Model

The remarkable performance of large multimodal models (LMMs) has attracted significant interest from the image segmentation community. To align with the next-token-prediction paradigm, current LMM-driven segmentation methods either use object boundary points to represent masks or introduce special segmentation tokens, whose hidden states are decoded by a segmentation model requiring the original image as input. However, these approaches often suffer from inadequate mask representation and complex architectures, limiting the potential of LMMs. In this work, we propose the Hierarchical Mask Tokenizer (HiMTok), which represents segmentation masks with up to 32 tokens and eliminates the need for the original image during mask de-tokenization. HiMTok allows for compact and coarse-to-fine mask representations, aligning well with the LLM next-token-prediction paradigm and facilitating the direct acquisition of segmentation capabilities. We develop a 3-stage training recipe for progressive learning of segmentation and visual capabilities, featuring a hierarchical mask loss for effective coarse-to-fine learning. Additionally, we enable bidirectional information flow, allowing conversion between bounding boxes and mask tokens to fully leverage multi-task training potential. Extensive experiments demonstrate that our method achieves state-of-the-art performance across various segmentation tasks,while also enhancing visual grounding and maintaining overall visual understanding.

  • 5 authors
·
Mar 17, 2025

pyMEAL: A Multi-Encoder Augmentation-Aware Learning for Robust and Generalizable Medical Image Translation

Medical imaging is critical for diagnostics, but clinical adoption of advanced AI-driven imaging faces challenges due to patient variability, image artifacts, and limited model generalization. While deep learning has transformed image analysis, 3D medical imaging still suffers from data scarcity and inconsistencies due to acquisition protocols, scanner differences, and patient motion. Traditional augmentation uses a single pipeline for all transformations, disregarding the unique traits of each augmentation and struggling with large data volumes. To address these challenges, we propose a Multi-encoder Augmentation-Aware Learning (MEAL) framework that leverages four distinct augmentation variants processed through dedicated encoders. Three fusion strategies such as concatenation (CC), fusion layer (FL), and adaptive controller block (BD) are integrated to build multi-encoder models that combine augmentation-specific features before decoding. MEAL-BD uniquely preserves augmentation-aware representations, enabling robust, protocol-invariant feature learning. As demonstrated in a Computed Tomography (CT)-to-T1-weighted Magnetic Resonance Imaging (MRI) translation study, MEAL-BD consistently achieved the best performance on both unseen- and predefined-test data. On both geometric transformations (like rotations and flips) and non-augmented inputs, MEAL-BD outperformed other competing methods, achieving higher mean peak signal-to-noise ratio (PSNR) and structural similarity index measure (SSIM) scores. These results establish MEAL as a reliable framework for preserving structural fidelity and generalizing across clinically relevant variability. By reframing augmentation as a source of diverse, generalizable features, MEAL supports robust, protocol-invariant learning, advancing clinically reliable medical imaging solutions.

  • 6 authors
·
May 30, 2025

Novel quantitative indicators of digital ophthalmoscopy image quality

With the advent of smartphone indirect ophthalmoscopy, teleophthalmology - the use of specialist ophthalmology assets at a distance from the patient - has experienced a breakthrough, promising enormous benefits especially for healthcare in distant, inaccessible or opthalmologically underserved areas, where specialists are either unavailable or too few in number. However, accurate teleophthalmology requires high-quality ophthalmoscopic imagery. This paper considers three feature families - statistical metrics, gradient-based metrics and wavelet transform coefficient derived indicators - as possible metrics to identify unsharp or blurry images. By using standard machine learning techniques, the suitability of these features for image quality assessment is confirmed, albeit on a rather small data set. With the increased availability and decreasing cost of digital ophthalmoscopy on one hand and the increased prevalence of diabetic retinopathy worldwide on the other, creating tools that can determine whether an image is likely to be diagnostically suitable can play a significant role in accelerating and streamlining the teleophthalmology process. This paper highlights the need for more research in this area, including the compilation of a diverse database of ophthalmoscopic imagery, annotated with quality markers, to train the Point of Acquisition error detection algorithms of the future.

  • 1 authors
·
Mar 6, 2019

CLBench-V: Evaluating Multimodal Context Learning from Grounding to Knowledge Acquisition

Real-world tasks often require models to learn from task-specific context rather than relying only on pre-trained knowledge. While recent work has highlighted this capability as context learning, existing evaluations mainly focus on textual contexts. In many practical settings, however, the context to be learned from is multimodal: scientific findings are conveyed through figures and tables, financial indicators are scattered across converted reports, and spatial decisions depend on maps, scenes, or web pages. We introduce CLBench-V, a benchmark for multimodal context learning that addresses the difficulty of localizing where context use breaks down by organizing tasks around three dimensions: context grounding, new information application, and new knowledge learning. CLBench-V combines converted public benchmarks with newly constructed datasets spanning domains such as science, finance, long-document understanding, spatial reasoning, and web-based visual question answering. To reduce the cost of constructing domain-specific context-learning tasks, we further use automated construction and filtering procedures for our newly built datasets. Across 3,443 instances and six recent multimodal models, the best overall score is only 0.2847, indicating that multimodal context learning remains far from saturated. Moreover, InternVL3.5-30B-A3B performs best on context grounding and new knowledge learning, while Qwen3.5-Plus performs best on new information application. We further analyze judge reliability, context length, image count, and representative failure cases. Code is available at https://github.com/IamLihua/CLBench-V.

  • 6 authors
·
Jul 27 2

NeuroCBIR: A Fast and Accurate Image Retrieval System for Whole-Brain and Region-Specific MRI

Content-based image retrieval (CBIR) in neuroimaging enables the identification of structurally similar brain scans, supporting diagnosis, prognosis, and treatment planning; however, existing methods are often limited to small datasets, single brain regions, or coarse class labels, thereby restricting their clinical utility and generalizability. Here, we present NeuroCBIR, a framework for fast and flexible retrieval of both whole-brain and region-specific 3D T1w MRI scans. A total of 103 cortical and subcortical regions are extracted to enable both whole-brain and region-level queries. NeuroCBIR leverages latent representations learned by a variational autoencoder (VAE) combined with contrastive learning, producing scan-specific embeddings that capture anatomical patterns. These embeddings were evaluated for subject re-identification, zero-shot age prediction, and zero-shot multi-class pathology stratification. Re-identification performance was high across both whole-brain and brain-region levels (mean average precision across the top-5 retrieved images (mAP@5) >= 98.4%), with robust generalization across datasets and acquisition conditions. While NeuroCBIR is not trained for age prediction or pathology stratification, zero-shot evaluations for these two tasks demonstrate that the embeddings encode meaningful information for downstream tasks. Embedding extraction on a 4-core CPU required approximately 18.7 s per scan, whereas similarity search was effectively instantaneous (less than 0.01 s). NeuroCBIR is publicly available for brain MRI with more than 26,000 precomputed T1w MRI embeddings. It supports reproducible research, region-specific flexibility, and clinically meaningful personalized diagnostic support. The software is available at https://github.com/minnelab/NeuroCBIR.

  • 6 authors
·
Oct 4

MedQ-Bench: Evaluating and Exploring Medical Image Quality Assessment Abilities in MLLMs

Medical Image Quality Assessment (IQA) serves as the first-mile safety gate for clinical AI, yet existing approaches remain constrained by scalar, score-based metrics and fail to reflect the descriptive, human-like reasoning process central to expert evaluation. To address this gap, we introduce MedQ-Bench, a comprehensive benchmark that establishes a perception-reasoning paradigm for language-based evaluation of medical image quality with Multi-modal Large Language Models (MLLMs). MedQ-Bench defines two complementary tasks: (1) MedQ-Perception, which probes low-level perceptual capability via human-curated questions on fundamental visual attributes; and (2) MedQ-Reasoning, encompassing both no-reference and comparison reasoning tasks, aligning model evaluation with human-like reasoning on image quality. The benchmark spans five imaging modalities and over forty quality attributes, totaling 2,600 perceptual queries and 708 reasoning assessments, covering diverse image sources including authentic clinical acquisitions, images with simulated degradations via physics-based reconstructions, and AI-generated images. To evaluate reasoning ability, we propose a multi-dimensional judging protocol that assesses model outputs along four complementary axes. We further conduct rigorous human-AI alignment validation by comparing LLM-based judgement with radiologists. Our evaluation of 14 state-of-the-art MLLMs demonstrates that models exhibit preliminary but unstable perceptual and reasoning skills, with insufficient accuracy for reliable clinical use. These findings highlight the need for targeted optimization of MLLMs in medical IQA. We hope that MedQ-Bench will catalyze further exploration and unlock the untapped potential of MLLMs for medical image quality evaluation.

  • 20 authors
·
Oct 2, 2025 2

ATOMMIC: An Advanced Toolbox for Multitask Medical Imaging Consistency to facilitate Artificial Intelligence applications from acquisition to analysis in Magnetic Resonance Imaging

AI is revolutionizing MRI along the acquisition and processing chain. Advanced AI frameworks have been developed to apply AI in various successive tasks, such as image reconstruction, quantitative parameter map estimation, and image segmentation. Existing frameworks are often designed to perform tasks independently or are focused on specific models or datasets, limiting generalization. We introduce ATOMMIC, an open-source toolbox that streamlines AI applications for accelerated MRI reconstruction and analysis. ATOMMIC implements several tasks using DL networks and enables MultiTask Learning (MTL) to perform related tasks integrated, targeting generalization in the MRI domain. We first review the current state of AI frameworks for MRI through a comprehensive literature search and by parsing 12,479 GitHub repositories. We benchmark 25 DL models on eight publicly available datasets to present distinct applications of ATOMMIC on accelerated MRI reconstruction, image segmentation, quantitative parameter map estimation, and joint accelerated MRI reconstruction and image segmentation utilizing MTL. Our findings demonstrate that ATOMMIC is the only MTL framework with harmonized complex-valued and real-valued data support. Evaluations on single tasks show that physics-based models, which enforce data consistency by leveraging the physical properties of MRI, outperform other models in reconstructing highly accelerated acquisitions. Physics-based models that produce high reconstruction quality can accurately estimate quantitative parameter maps. When high-performing reconstruction models are combined with robust segmentation networks utilizing MTL, performance is improved in both tasks. ATOMMIC facilitates MRI reconstruction and analysis by standardizing workflows, enhancing data interoperability, integrating unique features like MTL, and effectively benchmarking DL models.

  • 4 authors
·
Apr 30, 2024

Deep Generative Adversarial Network for Occlusion Removal from a Single Image

Nowadays, the enhanced capabilities of in-expensive imaging devices have led to a tremendous increase in the acquisition and sharing of multimedia content over the Internet. Despite advances in imaging sensor technology, annoying conditions like occlusions hamper photography and may deteriorate the performance of applications such as surveillance, detection, and recognition. Occlusion segmentation is difficult because of scale variations, illumination changes, and so on. Similarly, recovering a scene from foreground occlusions also poses significant challenges due to the complexity of accurately estimating the occluded regions and maintaining coherence with the surrounding context. In particular, image de-fencing presents its own set of challenges because of the diverse variations in shape, texture, color, patterns, and the often cluttered environment. This study focuses on the automatic detection and removal of occlusions from a single image. We propose a fully automatic, two-stage convolutional neural network for fence segmentation and occlusion completion. We leverage generative adversarial networks (GANs) to synthesize realistic content, including both structure and texture, in a single shot for inpainting. To assess zero-shot generalization, we evaluated our trained occlusion detection model on our proposed fence-like occlusion segmentation dataset. The dataset can be found on GitHub.

  • 3 authors
·
Sep 20, 2024

Training-free Composite Scene Generation for Layout-to-Image Synthesis

Recent breakthroughs in text-to-image diffusion models have significantly advanced the generation of high-fidelity, photo-realistic images from textual descriptions. Yet, these models often struggle with interpreting spatial arrangements from text, hindering their ability to produce images with precise spatial configurations. To bridge this gap, layout-to-image generation has emerged as a promising direction. However, training-based approaches are limited by the need for extensively annotated datasets, leading to high data acquisition costs and a constrained conceptual scope. Conversely, training-free methods face challenges in accurately locating and generating semantically similar objects within complex compositions. This paper introduces a novel training-free approach designed to overcome adversarial semantic intersections during the diffusion conditioning phase. By refining intra-token loss with selective sampling and enhancing the diffusion process with attention redistribution, we propose two innovative constraints: 1) an inter-token constraint that resolves token conflicts to ensure accurate concept synthesis; and 2) a self-attention constraint that improves pixel-to-pixel relationships. Our evaluations confirm the effectiveness of leveraging layout information for guiding the diffusion process, generating content-rich images with enhanced fidelity and complexity. Code is available at https://github.com/Papple-F/csg.git.

  • 3 authors
·
Jul 18, 2024

OpenUS: A Fully Open-Source Foundation Model for Ultrasound Image Analysis via Self-Adaptive Masked Contrastive Learning

Ultrasound (US) is one of the most widely used medical imaging modalities, thanks to its low cost, portability, real-time feedback, and absence of ionizing radiation. However, US image interpretation remains highly operator-dependent and varies significantly across anatomical regions, acquisition protocols, and device types. These variations, along with unique challenges such as speckle, low contrast, and limited standardized annotations, hinder the development of generalizable, label-efficient ultrasound AI models. In this paper, we propose OpenUS, the first reproducible, open-source ultrasound foundation model built on a large collection of public data. OpenUS employs a vision Mamba backbone, capturing both local and global long-range dependencies across the image. To extract rich features during pre-training, we introduce a novel self-adaptive masking framework that combines contrastive learning with masked image modeling. This strategy integrates the teacher's attention map with student reconstruction loss, adaptively refining clinically-relevant masking to enhance pre-training effectiveness. OpenUS also applies a dynamic learning schedule to progressively adjust the difficulty of the pre-training process. To develop the foundation model, we compile the largest to-date public ultrasound dataset comprising over 308K images from 42 publicly available datasets, covering diverse anatomical regions, institutions, imaging devices, and disease types. Our pre-trained OpenUS model can be easily adapted to specific downstream tasks by serving as a backbone for label-efficient fine-tuning. Code is available at https://github.com/XZheng0427/OpenUS.

Transformed Low-rank Adaptation via Tensor Decomposition and Its Applications to Text-to-image Models

Parameter-Efficient Fine-Tuning (PEFT) of text-to-image models has become an increasingly popular technique with many applications. Among the various PEFT methods, Low-Rank Adaptation (LoRA) and its variants have gained significant attention due to their effectiveness, enabling users to fine-tune models with limited computational resources. However, the approximation gap between the low-rank assumption and desired fine-tuning weights prevents the simultaneous acquisition of ultra-parameter-efficiency and better performance. To reduce this gap and further improve the power of LoRA, we propose a new PEFT method that combines two classes of adaptations, namely, transform and residual adaptations. In specific, we first apply a full-rank and dense transform to the pre-trained weight. This learnable transform is expected to align the pre-trained weight as closely as possible to the desired weight, thereby reducing the rank of the residual weight. Then, the residual part can be effectively approximated by more compact and parameter-efficient structures, with a smaller approximation error. To achieve ultra-parameter-efficiency in practice, we design highly flexible and effective tensor decompositions for both the transform and residual adaptations. Additionally, popular PEFT methods such as DoRA can be summarized under this transform plus residual adaptation scheme. Experiments are conducted on fine-tuning Stable Diffusion models in subject-driven and controllable generation. The results manifest that our method can achieve better performances and parameter efficiency compared to LoRA and several baselines.

  • 5 authors
·
Jan 15, 2025

The Lift Spectrum: How Measurement-to-Space Adaptivity Shapes Robustness in Image-Free Single-Pixel Sensing

Single-pixel sensing encodes a scene as a short sequence of coded measurements, and image-free methods infer the task directly from that sequence. Removing reconstruction does not remove the difficulty: it relocates it to the lift, the map from 1D measurements to a 2D representation, which prior work treats as a trivial reshape. We recast the lift as the central design axis of image-free sensing and order methods by how strongly it adapts to its input: a fixed-physics inverse (reconstruct-then-segment), a learned static projection, or a content-adaptive retrieval; position on this lift spectrum predicts behavior as acquisition degrades. The spatiotemporal soft-fusion (STSF) network pairs a probe-selected recurrent encoder with a cross-attention lift chosen by a parameter-matched ablation, ahead of its U-Net++ decoder, and trains under task-prioritized loss scheduling (TPLS), a scheduled reconstruction prior. In simulation, STSF+TPLS surpasses the prior image-free baseline on three datasets at 3.13% sampling (+3.2 to +9.9 pp foreground mIoU) and plateaus down to 0.39%. The strongest clean-trained reconstruct-then-segment baseline wins the noiseless limit, but under calibrated measurement noise image-free inference overtakes it, for a measured reason: the reconstruction pipeline amplifies the identical measurement noise before its segmenter reads it. Each region fails in its own signature: collapse, imprinting, or coarsening. STSF+TPLS transfers without fine-tuning to a real single-pixel bench as a proof of concept, at about 14 ms per mask. Charting the lift turns a scattered design space into a map of which lift to deploy at each operating point. Code and pretrained weights: https://github.com/Hanyuyuan6/STSF-TPLS

  • 11 authors
·
Jul 23

LoRetta: A Foundation Model and Extensive Dataset for Global-Scale Remote Sensing Dense Image Matching

Dense image matching establishes pixel-wise correspondences and underpins broad applications in computer vision and photogrammetry. However, extending dense matching to global-scale remote sensing remains challenging because image pairs may differ in acquisition time, season, viewpoint, spatial resolution, and land-cover state. The resulting large geometric offsets, partial overlap, and intrinsically unmatchable regions make direct dense correspondence prediction unreliable and inefficient. We thus reformulate dense matching as localization-and-registration: first localizing the matchable overlap and affine geometry, then refining dense residuals within the aligned frame. Based on this formulation, we propose LoRetta, a foundation model coupling matchability-aware affine localization with guided dense registration. We also introduce LEVIR-GM, a global-scale multi-temporal optical matching benchmark with dataset-native matchability labels (103K aligned, 827K augmented pairs, six continents, five years, 0.5-1024 m resolution). We further establish a unified evaluation protocol for sparse, semi-dense, and dense matchers. On LEVIR-GM, LoRetta achieves an area under the curve (AUC) of 83.3%, outperforming the strongest baseline RoMa v2 by 1.6 points, with larger percentage of correct keypoints (PCK) gains of 6.5 and 8.2 points at 1 and 2 pixels, while reducing inference latency by 47.8%. Astronaut-to-satellite and unmanned aerial vehicle (UAV)-to-satellite geolocalization experiments further demonstrate its transferability as a reusable geometric aligner.

  • 4 authors
·
Aug 3

From Corpora to Co-Evolving Capabilities: Capability-Centric Data Design for Generalist Image Generation

Large-scale image generation has benefited from advances in data scale, quality, rebalancing, and recaptioning, yet conventional pipelines typically optimize task-specific datasets in isolation. A central challenge is not only how to curate each task-specific corpus, but also how to organize heterogeneous supervision according to the dependencies among generative capabilities. We present a capability-driven data infrastructure that couples capability-specific supervision construction with capability-aligned curriculum scheduling. Its three specialized yet interoperable data engines build complementary relational supervision for text-image grounding, inter-image transformation, and image-knowledge association, while caption experts align T2I and editing supervision across tasks and granularities. A multi-stage curriculum jointly evolves task composition, visual-concept distribution, data quality, and image resolution along the dependency order of capability acquisition, with capability-aware evaluation closing the loop through targeted retrieval, expert construction, and gap-aware resampling. At scale, the framework curates a 440M-image T2I corpus, 120M editing pairs, and over 27M image-entity pairs. With this infrastructure, we train multimodal diffusion models at two scales from scratch, with 3B and 6B sizes respectively. We conduct quantitative evaluation on CPI-Bench, along with qualitative evaluations across diverse text-to-image and editing scenarios. Experimental results present broad visual coverage, versatile rendering, and effective transfer across generative capabilities.

alibabagroup alibaba
·
Aug 17 2

CFNet: Optimizing Remote Sensing Change Detection through Content-Aware Enhancement

Change detection is a crucial and widely applied task in remote sensing, aimed at identifying and analyzing changes occurring in the same geographical area over time. Due to variability in acquisition conditions, bi-temporal remote sensing images often exhibit significant differences in image style. Even with the powerful generalization capabilities of DNNs, these unpredictable style variations between bi-temporal images inevitably affect model's ability to accurately detect changed areas. To address issue above, we propose the Content Focuser Network (CFNet), which takes content-aware strategy as a key insight. CFNet employs EfficientNet-B5 as the backbone for feature extraction. To enhance the model's focus on the content features of images while mitigating the misleading effects of style features, we develop a constraint strategy that prioritizes the content features of bi-temporal images, termed Content-Aware. Furthermore, to enable the model to flexibly focus on changed and unchanged areas according to the requirements of different stages, we design a reweighting module based on the cosine distance between bi-temporal image features, termed Focuser. CFNet achieve outstanding performance across three well-known change detection datasets: CLCD (F1: 81.41%, IoU: 68.65%), LEVIR-CD (F1: 92.18%, IoU: 85.49%), and SYSU-CD (F1: 82.89%, IoU: 70.78%). The code and pretrained models of CFNet are publicly released at https://github.com/wifiBlack/CFNet.

  • 3 authors
·
Mar 11, 2025

SynthRAD2025 Grand Challenge dataset: generating synthetic CTs for radiotherapy

Medical imaging is essential in modern radiotherapy, supporting diagnosis, treatment planning, and monitoring. Synthetic imaging, particularly synthetic computed tomography (sCT), is gaining traction in radiotherapy. The SynthRAD2025 dataset and Grand Challenge promote advancements in sCT generation by providing a benchmarking platform for algorithms using cone-beam CT (CBCT) and magnetic resonance imaging (MRI). The dataset includes 2362 cases: 890 MRI-CT and 1472 CBCT-CT pairs from head-and-neck, thoracic, and abdominal cancer patients treated at five European university medical centers (UMC Groningen, UMC Utrecht, Radboud UMC, LMU University Hospital Munich, and University Hospital of Cologne). Data were acquired with diverse scanners and protocols. Pre-processing, including rigid and deformable image registration, ensures high-quality, modality-aligned images. Extensive quality assurance validates image consistency and usability. All imaging data is provided in MetaImage (.mha) format, ensuring compatibility with medical image processing tools. Metadata, including acquisition parameters and registration details, is available in structured CSV files. To maintain dataset integrity, SynthRAD2025 is divided into training (65%), validation (10%), and test (25%) sets. The dataset is accessible at https://doi.org/10.5281/zenodo.14918089 under the SynthRAD2025 collection. This dataset supports benchmarking and the development of synthetic imaging techniques for radiotherapy applications. Use cases include sCT generation for MRI-only and MR-guided photon/proton therapy, CBCT-based dose calculations, and adaptive radiotherapy workflows. By integrating diverse acquisition settings, SynthRAD2025 fosters robust, generalizable image synthesis algorithms, advancing personalized cancer care and adaptive radiotherapy.

  • 19 authors
·
Feb 24, 2025

Puzzle Similarity: A Perceptually-guided No-Reference Metric for Artifact Detection in 3D Scene Reconstructions

Modern reconstruction techniques can effectively model complex 3D scenes from sparse 2D views. However, automatically assessing the quality of novel views and identifying artifacts is challenging due to the lack of ground truth images and the limitations of no-reference image metrics in predicting detailed artifact maps. The absence of such quality metrics hinders accurate predictions of the quality of generated views and limits the adoption of post-processing techniques, such as inpainting, to enhance reconstruction quality. In this work, we propose a new no-reference metric, Puzzle Similarity, which is designed to localize artifacts in novel views. Our approach utilizes image patch statistics from the input views to establish a scene-specific distribution that is later used to identify poorly reconstructed regions in the novel views. We test and evaluate our method in the context of 3D reconstruction; to this end, we collected a novel dataset of human quality assessment in unseen reconstructed views. Through this dataset, we demonstrate that our method can not only successfully localize artifacts in novel views, correlating with human assessment, but do so without direct references. Surprisingly, our metric outperforms both no-reference metrics and popular full-reference image metrics. We can leverage our new metric to enhance applications like automatic image restoration, guided acquisition, or 3D reconstruction from sparse inputs.

  • 3 authors
·
Nov 26, 2024

X-Splat: Gaussian Splatting for 3D CBCT Generation from Single Panoramic Radiograph

Generating a 3D dental volume from a single panoramic radiograph (PXR) could provide a low-radiation alternative to Cone-Beam Computed Tomography (CBCT), but the problem is highly underdetermined: panoramic acquisition integrates 3D attenuation along curved X-ray paths into a 2D image, leaving depth-resolved anatomy unobserved. Existing implicit and generative approaches often produce oversmoothed geometry or anatomically inconsistent hallucinations, lacking geometry-driven supervision and relying on smooth representations unable to precisely localize sharp anatomical boundaries. We propose X-Splat, the first Gaussian Splatting framework for generating CBCT-like 3D dental volumes from a single PXR. X-Splat uses the known panoramic acquisition geometry as a generation scaffold: learnable anisotropic Gaussian primitives are initialized along the X-ray paths that formed the input image and adjusted in a single feed-forward pass, constrained by Beer-Lambert reprojection and multi-view radiographic training supervision. A lightweight residual refiner adds dataset-level anatomical priors without overriding the geometry already resolved by the Gaussians. We train on synthetic PXR-CBCT pairs, enabling direct volumetric supervision without paired real scans. We further introduce segmentation-based geometry-aware metrics, providing the first evaluation of PXR-based generation over maxillofacial anatomy. X-Splat outperforms NeRF- and GAN-based baselines, recovering individual teeth, cortical boundaries, and alveolar structure, including the mandibular canal which prior methods fail to reconstruct. Code will be available at https://github.com/tomek1911/X-Splat

  • 5 authors
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Jul 1

Experimental Design for Multi-Channel Imaging via Task-Driven Feature Selection

This paper presents a data-driven, task-specific paradigm for experimental design, to shorten acquisition time, reduce costs, and accelerate the deployment of imaging devices. Current approaches in experimental design focus on model-parameter estimation and require specification of a particular model, whereas in imaging, other tasks may drive the design. Furthermore, such approaches often lead to intractable optimization problems in real-world imaging applications. Here we present a new paradigm for experimental design that simultaneously optimizes the design (set of image channels) and trains a machine-learning model to execute a user-specified image-analysis task. The approach obtains data densely-sampled over the measurement space (many image channels) for a small number of acquisitions, then identifies a subset of channels of prespecified size that best supports the task. We propose a method: TADRED for TAsk-DRiven Experimental Design in imaging, to identify the most informative channel-subset whilst simultaneously training a network to execute the task given the subset. Experiments demonstrate the potential of TADRED in diverse imaging applications: several clinically-relevant tasks in magnetic resonance imaging; and remote sensing and physiological applications of hyperspectral imaging. Results show substantial improvement over classical experimental design, two recent application-specific methods within the new paradigm, and state-of-the-art approaches in supervised feature selection. We anticipate further applications of our approach. Code is available: https://github.com/sbb-gh/experimental-design-multichannel

  • 3 authors
·
Oct 13, 2022

MERLiN: Single-Shot Material Estimation and Relighting for Photometric Stereo

Photometric stereo typically demands intricate data acquisition setups involving multiple light sources to recover surface normals accurately. In this paper, we propose MERLiN, an attention-based hourglass network that integrates single image-based inverse rendering and relighting within a single unified framework. We evaluate the performance of photometric stereo methods using these relit images and demonstrate how they can circumvent the underlying challenge of complex data acquisition. Our physically-based model is trained on a large synthetic dataset containing complex shapes with spatially varying BRDF and is designed to handle indirect illumination effects to improve material reconstruction and relighting. Through extensive qualitative and quantitative evaluation, we demonstrate that the proposed framework generalizes well to real-world images, achieving high-quality shape, material estimation, and relighting. We assess these synthetically relit images over photometric stereo benchmark methods for their physical correctness and resulting normal estimation accuracy, paving the way towards single-shot photometric stereo through physically-based relighting. This work allows us to address the single image-based inverse rendering problem holistically, applying well to both synthetic and real data and taking a step towards mitigating the challenge of data acquisition in photometric stereo.

  • 3 authors
·
Sep 1, 2024

ImagePairs: Realistic Super Resolution Dataset via Beam Splitter Camera Rig

Super Resolution is the problem of recovering a high-resolution image from a single or multiple low-resolution images of the same scene. It is an ill-posed problem since high frequency visual details of the scene are completely lost in low-resolution images. To overcome this, many machine learning approaches have been proposed aiming at training a model to recover the lost details in the new scenes. Such approaches include the recent successful effort in utilizing deep learning techniques to solve super resolution problem. As proven, data itself plays a significant role in the machine learning process especially deep learning approaches which are data hungry. Therefore, to solve the problem, the process of gathering data and its formation could be equally as vital as the machine learning technique used. Herein, we are proposing a new data acquisition technique for gathering real image data set which could be used as an input for super resolution, noise cancellation and quality enhancement techniques. We use a beam-splitter to capture the same scene by a low resolution camera and a high resolution camera. Since we also release the raw images, this large-scale dataset could be used for other tasks such as ISP generation. Unlike current small-scale dataset used for these tasks, our proposed dataset includes 11,421 pairs of low-resolution high-resolution images of diverse scenes. To our knowledge this is the most complete dataset for super resolution, ISP and image quality enhancement. The benchmarking result shows how the new dataset can be successfully used to significantly improve the quality of real-world image super resolution.

  • 8 authors
·
Apr 17, 2020

SynthRAD2023 Grand Challenge dataset: generating synthetic CT for radiotherapy

Purpose: Medical imaging has become increasingly important in diagnosing and treating oncological patients, particularly in radiotherapy. Recent advances in synthetic computed tomography (sCT) generation have increased interest in public challenges to provide data and evaluation metrics for comparing different approaches openly. This paper describes a dataset of brain and pelvis computed tomography (CT) images with rigidly registered CBCT and MRI images to facilitate the development and evaluation of sCT generation for radiotherapy planning. Acquisition and validation methods: The dataset consists of CT, CBCT, and MRI of 540 brains and 540 pelvic radiotherapy patients from three Dutch university medical centers. Subjects' ages ranged from 3 to 93 years, with a mean age of 60. Various scanner models and acquisition settings were used across patients from the three data-providing centers. Details are available in CSV files provided with the datasets. Data format and usage notes: The data is available on Zenodo (https://doi.org/10.5281/zenodo.7260705) under the SynthRAD2023 collection. The images for each subject are available in nifti format. Potential applications: This dataset will enable the evaluation and development of image synthesis algorithms for radiotherapy purposes on a realistic multi-center dataset with varying acquisition protocols. Synthetic CT generation has numerous applications in radiation therapy, including diagnosis, treatment planning, treatment monitoring, and surgical planning.

  • 9 authors
·
Mar 28, 2023

ViRC: Enhancing Visual Interleaved Mathematical CoT with Reason Chunking

CoT has significantly enhanced the reasoning ability of LLMs while it faces challenges when extended to multimodal domains, particularly in mathematical tasks. Existing MLLMs typically perform textual reasoning solely from a single static mathematical image, overlooking dynamic visual acquisition during reasoning. In contrast, humans repeatedly examine visual image and employ step-by-step reasoning to prove intermediate propositions. This strategy of decomposing the problem-solving process into key logical nodes adheres to Miller's Law in cognitive science. Inspired by this insight, we propose a ViRC framework for multimodal mathematical tasks, introducing a Reason Chunking mechanism that structures multimodal mathematical CoT into consecutive Critical Reasoning Units (CRUs) to simulate human expert problem-solving patterns. CRUs ensure intra-unit textual coherence for intermediate proposition verification while integrating visual information across units to generate subsequent propositions and support structured reasoning. To this end, we present CRUX dataset by using three visual tools and four reasoning patterns to provide explicitly annotated CRUs across multiple reasoning paths for each mathematical problem. Leveraging the CRUX dataset, we propose a progressive training strategy inspired by human cognitive learning, which includes Instructional SFT, Practice SFT, and Strategic RL, aimed at further strengthening the Reason Chunking ability of the model. The resulting ViRC-7B model achieves a 18.8% average improvement over baselines across multiple mathematical benchmarks. Code is available at https://github.com/Leon-LihongWang/ViRC.

  • 9 authors
·
Dec 16, 2025

A Tutorial on MRI Reconstruction: From Modern Methods to Clinical Implications

MRI is an indispensable clinical tool, offering a rich variety of tissue contrasts to support broad diagnostic and research applications. Clinical exams routinely acquire multiple structural sequences that provide complementary information for differential diagnosis, while research protocols often incorporate advanced functional, diffusion, spectroscopic, and relaxometry sequences to capture multidimensional insights into tissue structure and composition. However, these capabilities come at the cost of prolonged scan times, which reduce patient throughput, increase susceptibility to motion artifacts, and may require trade-offs in image quality or diagnostic scope. Over the last two decades, advances in image reconstruction algorithms--alongside improvements in hardware and pulse sequence design--have made it possible to accelerate acquisitions while preserving diagnostic quality. Central to this progress is the ability to incorporate prior information to regularize the solutions to the reconstruction problem. In this tutorial, we overview the basics of MRI reconstruction and highlight state-of-the-art approaches, beginning with classical methods that rely on explicit hand-crafted priors, and then turning to deep learning methods that leverage a combination of learned and crafted priors to further push the performance envelope. We also explore the translational aspects and eventual clinical implications of these methods. We conclude by discussing future directions to address remaining challenges in MRI reconstruction. The tutorial is accompanied by a Python toolbox (https://github.com/tutorial-MRI-recon/tutorial) to demonstrate select methods discussed in the article.

  • 7 authors
·
Jul 22, 2025